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Vietnam and Cambodia Highlights

Climb aboard the Mekong Serenity for an immersive 15-day APT Touring River Cruise from Siem Reap to Ho Chi Minh City.

Enjoy hikes, bike rides, scenic sailings and much more on a hand-crafted itinerary, designed to give you a customisable and unforgettable Mekong River Cruise.

Recline aboard the luxury Mekong Serenity for a first-class experience; complete with 6-course dining and a host of organised on-board demonstrations, classes and activities.

4.7
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from 322 reviews
  • Cruise Line: APT Touring
  • Ship: Mekong Serenity
  • Duration: 14 Nights
  • Departure: Jan - Apr
AVG PER PERSON*
£5,245
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Vietnam and Cambodia Highlights Cruise Prices

Starting price per person
Jan 19, 2026
£5,245
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Jan 26, 2026
£5,245
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Feb 02, 2026
£6,345
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Feb 09, 2026
£6,345
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Feb 16, 2026
£6,345
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Feb 23, 2026
£6,345
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Mar 02, 2026
£6,545
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Mar 09, 2026
£6,245
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Mar 16, 2026
£6,245
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Mar 23, 2026
£6,245
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Mar 30, 2026
£6,245
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Apr 06, 2026
£5,945
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Apr 13, 2026
£5,745
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Apr 20, 2026
£5,345
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More Dates

Vietnam and Cambodia Highlights Cruise Itinerary

From World Heritage listed sites to cathedrals, museums and scenic sailings – on this adventure, you’ll work your way through a meticulously crafted itinerary packed with Signature Experiences and Freedom of Choice excursions.

Signature Experiences Marked*

    Day 1

    London (DEPARTURE)

    Depart from London Heathrow on your flight to Cambodia.

    Day 2

    Siem Reap (ARRIVAL)

    Transfer to your luxurious hotel in the heart of the city – enjoy the rest of the day at your leisure. Tonight, choose from a selection of local restaurants for dinner.

    Day 3

    Siem Reap

    Begin your day at the UNESCO-designated Angkor Archaeological Park – pay visits to Angkor Thom, Bayon Temple, the Terrace of Elephants, Terrace of the Leper King and Ta Prohm (AKA Tomb Raider Temple). Your Signature Experience* is a visit to the ODA – Opportunities of Development Through Art.

    Day 4

    Siem Reap

    Watch the sunrise from Angkor Archaeological Park’s Angkor Wat*, tour the well-preserved temple, treat yourself to a private visit to Theam’s Gallery* and choose between a tuk tuk ride to a Senteurs d’Angkor workshop, quad bike adventure, leisurely countryside bike tour, horse and cart ride or cooking class.

    Day 5

    Siem Reap / Kampong Cham / Koh Pen / Angkor Ban (EMBARK)

    Journey to Kampong Cham to embark the Mekong Serenity. Following lunch, discover the island of Koh Pen via tuk tuk*.

    Day 6

    Angkor Ban / Koh Oknha Tey / Phnom Penh

    Take a walking tour of Angkor Ban. Later, explore Koh Oknha Tey to gain insight into the traditional silk weaving process.

    Day 7

    Phnom Penh

    Dip your toe into history during an excursion to the Killing Fields and Tuol Sleng Genocide Museum or discover Phnom Penh via cyclo ride. Admire the National Museum, Royal Palace (with Silver Pagoda) or sample some local brews at two of the city’s craft breweries.

    Day 8

    Phnom Penh / Oudong / Koh Chen

    In Oudong, be treated to a Buddhist Blessing performed by monks at a local monastery*. Take a leisurely stroll through Koh Chen and visit some home workshops that make copperware.

    Day 9

    Phnom Penh / Tan Chau (BORDER CROSSING)

    Enjoy a day cruising across the Vietnamese border. Take part in our onboard presentations, fruit-carving demonstrations, cooking workshops and much more.

    Day 10

    Tan Chau / Evergreen Island / Sa Dec

    Journey along the tiny tributaries that snake around Tan Chau via small boat. Glide past a floating fish farm, small shops and friendly locals. Pay a visit to a local rattan silk and rattan weaving workshop. Later, visit Evergreen Island.

    Day 11

    Sa Dec / Cai Be / My Tho

    Journey via tender boat to Sa Dec, tour the former home off Huynh Thuy Le and visit a traditional Cao Dai temple. Travel to the French Gothic Cathedral, colourful port area and a rice paper manufacturer.

    Day 12

    My Tho / Ho Chi Minh City (DISEMBARK)

    Choose between a leisurely walking discovery of the city, motorbike city ride, Tai Chi class or fun cooking class.

    Day 13

    Ho Chi Minh City

    Journey by speedboat to the Cu Chi Tunnels*, meet a Master Distiller at Lady Trieu Gin Distillery* and savour dinner at the highly acclaimed Vietnam House restaurant*.

    Day 14

    Ho Chi Minh City (DEPARTURE)

    After breakfast, transfer to Tan Son Nhat International Airport for your onward flight back to the UK.

    Day 15

    London (ARRIVAL)

    Arrive back in London.

    VIETNAM AND CAMBODIA HIGHLIGHTS CRUISE SHIPS

    Mekong Serenity

    Trustpilot Reviews

    VIETNAM AND CAMBODIA HIGHLIGHTS RIVER CRUISE HIGHLIGHTS

    Experience Vietnam and Cambodia like never before.

    Ha Long Bay

    Ho Chi Minh City

    Phnom Penh

    Angkor Wat

    Vietnam and Cambodia Highlights Deals

    Further explore the highlights Vietnam and Cambodia

    APT Touring
    Departure: Jan to Apr
    VISITING: London (DEPARTURE) Siem Reap (ARRIVAL) Siem Reap Siem Reap / Kampong Cham / Koh Pen / Angkor Ban (EMBARK) Angkor Ban / Koh Oknha Tey / Phnom Penh Phnom Penh Phnom Penh / Oudong / Koh Chen Phnom Penh / Tan Chau (BORDER CROSSING) Tan Chau / Evergreen Island / Sa Dec Sa Dec / Cai Be / My Tho My Tho / Ho Chi Minh City (DISEMBARK) Ho Chi Minh City Ho Chi Minh City (DEPARTURE) London (ARRIVAL)
    AVG PER PERSON* £ 5,245
    APT Touring
    Departure: Feb to Apr
    VISITING: London Arrive in Ho Chi Minh City Ho Chi Minh City Ho Chi Minh City, Da Nang, Hoi An Hoi An Hoi An, Hue Hue Hue, Hanoi Hanoi Hanoi, Tuan Chau, Embark Ship Ha Long Bay Ha Long Bay Ha Long Bay, Tuan Chau, Disembark Ship, Hanoi, Siem Reap Siem Reap Siem Reap, Kampong Cham, Embark Ship, Koh Pen, Angkor Ban Angkor Ban, Koh Oknha Tey, Phnom Penh Phnom Penh Phnom Penh, Oudong Phnom Penh, Border Crossing, Tan Chau Tan Chau, Evergreen Island, Sa Dec Sa Dec, Cai Be, My Tho My Tho, Disembark Ship, Depart for Ho Chi Minh City
    AVG PER PERSON* £ 8,345
    APT Touring
    Departure: January
    VISITING: London Hanoi Hanoi, Tuan Chau, Embark Ship, Halong Bay Ha Long Bay Halong Bay, Disembark Ship, Tuan Chau, Hanoi, Siem Reap Siem Reap Siem Reap, Kampong Cham, Embark Ship, Angkor Ban Angkor Ban, Oknha Tey Oknha Tey, Oudong, Koh Chen, Phnom Penh Phnom Penh Phnom Penh, Border Crossing, Tan Chau Tan Chau, Sa Dec Sa Dec, Cai Be, My Tho My Tho, Disembark Ship, Cu Chi Tunnels, Ho Chi Minh City Ho Chi Minh City Depart Ho Chi Minh City
    AVG PER PERSON* POA
    APT Touring
    Departure: Oct to Apr
    VISITING: London (DEPARTURE) Siem Reap (ARRIVAL) Siem Reap Siem Reap, Kampong Cham (EMBARK SHIP) Kampong Cham, Angkor Ban, Kok Oknha Tey Phnom Penh, Oudong, Koh Chen Phnom Penh Phnom Penh, Tan Chau (BORDER CROSSING) Tan Chau, Sa Dec Sa Dec, Cai Be, My Tho My Tho, Cu Chi Tunnels, Ho Chi Minh City (DISEMBARK SHIP) Ho Chi Minh City Ho Chi Minh City (DEPARTURE) London (ARRIVAL)
    AVG PER PERSON* £ 3,695
    APT Touring
    Departure:
    VISITING: London (DEPARTURE) Hanoi Hanoi / Ha Long Bay (EMBARK*) Ha Long Bay Hoi An (DISEMBARK*) Hoi An Hoi An / Hue Hue / Ho Chi Minh City Cu Chi Tunnels / Ho Chi Minh City Ho Chi Minh City / My Tho (EMBARK) Cai Be / Sa Dec Tan Chau (Border Crossing) Phnom Penh Oudong / Koh Chen Okna Tey Angkor Ban / Koh Pen Kampong Cham / Siem Reap / Angkor (DISEMBARK) Angkor / Siem Reap Siem Reap (DEPARTURE) London
    AVG PER PERSON* £ 5,695

    Vietnam and Cambodia Highlights Cruise Review

    “Really fun. The Signature Experiences were very impressive; such a wide array of opportunities. My suite aboard the Mekong Serenity was really lovely too; spacious and comfortable.”

    Stef Ashton, Manchester

    Vietnam and Cambodia Highlights FAQ

    How many days will be spent aboard the Mekong Serenity?

    The Mekong Serenity will act as your home for 7 nights of your journey.

    What are Signature Experiences?

    Once-in-a-lifetime opportunities offered exclusively to APT guests.

    How many crew members are aboard the ship?

    The Mekong Serenity hosts 44 crew members whom are dedicated to helping you achieve the best experience possible.

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