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Vietnam and Cambodia Highlights

Climb aboard the Mekong Serenity for an immersive 15-day adventure from Siem Reap to Ho Chi Minh City.

Enjoy hikes, bike rides, scenic sailings and much more on a hand-crafted itinerary, designed to give you a customisable and unforgettable experience.

Recline aboard the luxury Mekong Serenity for a first-class experience; complete with 6-course dining and a host of organised on-board demonstrations, classes and activities.

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from 322 reviews
  • Cruise Line: APT Touring
  • Ship: Mekong Serenity
  • Duration: 14 Nights
  • Departure: Jul-Dec (2024) Jan-Mar (2025)
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Vietnam and Cambodia Highlights Cruise Itinerary

From World Heritage listed sites to cathedrals, museums and scenic sailings – on this adventure, you’ll work your way through a meticulously crafted itinerary packed with Signature Experiences and Freedom of Choice excursions.

Signature Experiences Marked*

Day 1


Depart from London Heathrow on your flight to Cambodia.

Day 2

Siem Reap (ARRIVAL)

Transfer to your luxurious hotel in the heart of the city – enjoy the rest of the day at your leisure. Tonight, choose from a selection of local restaurants for dinner.

Day 3

Siem Reap

Begin your day at the UNESCO-designated Angkor Archaeological Park – pay visits to Angkor Thom, Bayon Temple, the Terrace of Elephants, Terrace of the Leper King and Ta Prohm (AKA Tomb Raider Temple). Your Signature Experience* is a visit to the ODA – Opportunities of Development Through Art.

Day 4

Siem Reap

Watch the sunrise from Angkor Archaeological Park’s Angkor Wat*, tour the well-preserved temple, treat yourself to a private visit to Theam’s Gallery* and choose between a tuk tuk ride to a Senteurs d’Angkor workshop, quad bike adventure, leisurely countryside bike tour, horse and cart ride or cooking class.

Day 5

Siem Reap / Kampong Cham / Koh Pen / Angkor Ban (EMBARK)

Journey to Kampong Cham to embark the Mekong Serenity. Following lunch, discover the island of Koh Pen via tuk tuk*.

Day 6

Angkor Ban / Koh Oknha Tey / Phnom Penh

Take a walking tour of Angkor Ban. Later, explore Koh Oknha Tey to gain insight into the traditional silk weaving process.

Day 7

Phnom Penh

Dip your toe into history during an excursion to the Killing Fields and Tuol Sleng Genocide Museum or discover Phnom Penh via cyclo ride. Admire the National Museum, Royal Palace (with Silver Pagoda) or sample some local brews at two of the city’s craft breweries.

Day 8

Phnom Penh / Oudong / Koh Chen

In Oudong, be treated to a Buddhist Blessing performed by monks at a local monastery*. Take a leisurely stroll through Koh Chen and visit some home workshops that make copperware.

Day 9

Phnom Penh / Tan Chau (BORDER CROSSING)

Enjoy a day cruising across the Vietnamese border. Take part in our onboard presentations, fruit-carving demonstrations, cooking workshops and much more.

Day 10

Tan Chau / Evergreen Island / Sa Dec

Journey along the tiny tributaries that snake around Tan Chau via small boat. Glide past a floating fish farm, small shops and friendly locals. Pay a visit to a local rattan silk and rattan weaving workshop. Later, visit Evergreen Island.

Day 11

Sa Dec / Cai Be / My Tho

Journey via tender boat to Sa Dec, tour the former home off Huynh Thuy Le and visit a traditional Cao Dai temple. Travel to the French Gothic Cathedral, colourful port area and a rice paper manufacturer.

Day 12

My Tho / Ho Chi Minh City (DISEMBARK)

Choose between a leisurely walking discovery of the city, motorbike city ride, Tai Chi class or fun cooking class.

Day 13

Ho Chi Minh City

Journey by speedboat to the Cu Chi Tunnels*, meet a Master Distiller at Lady Trieu Gin Distillery* and savour dinner at the highly acclaimed Vietnam House restaurant*.

Day 14

Ho Chi Minh City (DEPARTURE)

After breakfast, transfer to Tan Son Nhat International Airport for your onward flight back to the UK.

Day 15

London (ARRIVAL)

Arrive back in London.

Vietnam and Cambodia Highlights Cruise Ships

Mekong Serenity

Recline aboard APT’s newest and most luxurious ship on the Mekong. Featuring 44 elegant suites, private outdoor balconies, indoor panoramic balconies and much more – this floating hotel is designed to cater to guests’ every whim.

Launched in 2023
44 Crew Members
Six-course Dining Experience

Trustpilot Reviews

Vietnam and Cambodia Highlights Deals

Further explore the highlights Vietnam and Cambodia

14 Nights
Jul Dec
Jan Mar

Vietnam and Cambodia Highlights

  • Angkor Ban / Koh Oknha Tey
  • Ho Chi Minh City
  • London
  • My Tho / Ho Chi Minh City
  • Phnom Penh
  • Phnom Penh / Oudong / Koh Chen
  • Sa Dec / Cai Be / My Tho
  • Siem Reap
  • Siem Reap / Kampong Cham / Embark Ship Koh Pen / Angkor Ban
  • Tan Chau / Evergreen Island / Sa Dec
£5,955pp Est. Price per person
  • Mekong Serenity  

Vietnam and Cambodia Highlights Cruise Review

“Really fun. The Signature Experiences were very impressive; such a wide array of opportunities. My suite aboard the Mekong Serenity was really lovely too; spacious and comfortable.”

Stef Ashton, Manchester

Vietnam and Cambodia Highlights FAQ

Find answers to some of the most common questions about river cruising here.

How many days will be spent aboard the Mekong Serenity?

The Mekong Serenity will act as your home for 7 nights of your journey.

What are Signature Experiences?

Once-in-a-lifetime opportunities offered exclusively to APT guests.

How many crew members are aboard the ship?

The Mekong Serenity hosts 44 crew members whom are dedicated to helping you achieve the best experience possible.

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